bone metastases reddit

He was fourth stage when he was diagnosed. bone metastases) are common and result in significant morbidity in patients with metastatic disease.Although the diagnosis is often straightforward, especially as in many cases there is a well-documented history of metastatic malignancy, sometimes they may mimic benign disease or other primary malignancies. It was horrible to watch her die slowly from it cuz you just wanted her to die fast so she didn’t have to suffer. Patients and Methods . New comments cannot be posted and votes cannot be cast, More posts from the interestingasfuck community, Press J to jump to the feed. The sites of bone metastases were the vertebrae (15/19, 79%), pelvis (3/19, 16%), ribs (3/19, 16%) and femur (2/19, 11%). Bone Metastases. Bone metastases have the potential to cause significant morbidity including pain, impairment of ambulation and reduced functional independence. There were bone metastases at diagnosis (0.51%, 13/2550) or at relapse (0.24%, 6/2550). Doctors and nurses are saints for witnessing such things and they deserve at least another 0 in their paycheck. My dad has lung cancer with several metastases (lung and lower spine mainly). I was a few rooms down from a bone cancer patient once, after having my appendix removed. Forty‐three patients (57.3%) also had extra‐osseous metastases. Reddit; Wechat; Summary. Bone metastases can be classified as lytic, blastic, or mixed depending on the activity of tumor-stimulated host osteoclasts and osteoblasts. Associated skeletal‐related events (SREs) cause severe pain, reduced quality of life and place a burden on health care resources. Google PET scan bone mets. Most of the patients received radiotherapy, chemotherapy or both, but 25 patients (33.3%) received palliative care only. Close. There is so much worse than death. Press question mark to learn the rest of the keyboard shortcuts. My grandpa died of the bone cancer you're talking about. Not only for myself, but for the people who have to watch, like I did. I'm with you: Kill me. He's been on keytruda for a while now and has been in a stable condition for the past months which I'm very thankful for . By using our Services or clicking I agree, you agree to our use of cookies. We know it’s a matter of time before something else fractures. This makes me so worried. The clinical treatment of bone metastasis from breast cancer is currently based on the systemic administration of antiresorptive agents, radiopharmaceuticals, and/or local treatments such as radiation therapy, radiofrequency ablation and surgery. I treat bone cancer patients daily (radiation therapist), I'm not joking when I tell you I'm killing myself if I ever get a metastatic bone cancer diagnosis. Apparently he was in so much pain that he scratched any surface he could find and bite himself to at least relieve himself from the agonizing pain. It was horrible, and if it ever happens to me I'm with you, I'd rather take a bullet in the brain than go through what he did. I'm also not a doctor, just a licensed radiation therapist in the midwest. That is not a joke or embellishment. consensual internet hug. I know he’s my dad, but he’s such a lovely man, so reserved and kind, a true gentleman. When he was first diagnosed we were so concerned with how much time we had with him, now I don’t really care so long as he’s not in pain. Bone metastases are sometimes found because they cause problems, but in some cases, they’re found before you have any symptoms. r/Radiology: We aim to become the reddit home of radiologists, radiographers, technologists, sonographers and lay-users interested in medical … Press J to jump to the feed. Google PET scan bone mets. log in sign up. The cancer is in his spine, ribs, pelvis and thigh. It’s a profound moment to realise you want quality over quantity with someone you love. It wasn't a whiny, complaining type of moaning. Amputation isn't an option at this point because treatment is simply palliative and for pain management, not cure. We were eight at the time. Reddit; Wechat; Abstract en. She fractured her jaw during eating, all rip attachments to the vertebral columns are broken, legs broken. Your doctor may do lab tests and imaging tests (like x-rays or bone scans) to see if and/or how far the cancer has spread. Likely better than our best science if we were to be honest. Other autopsy studies report bone me- tastases in 47 to 85 per cent of women dying from breast cancer, in 33 to 85 per cent of patients with prostatic cancer, and in 32 to 60 per cent of patients with lung cancer (86). I am with you. One day we had to attend an hour on the autopsy table where we had a guy with metastatic bone cancer that OD-ed with morphine (maybe even euthanised by a doctor or nurse). New comments cannot be posted and votes cannot be cast. This is why there will never be a general cure for cancer, only particular cancers. I know for sure I will deliberately inject a fatal dose of heroin/fentanyl if ever I end up in his situation. 302 comments. Background. Crossposted by 2 months ago. 16. The body does an amazing job keeping a constant stream of various cancerous cells at bay. Background: Currently bisphosphonates are often administered to patients with osteolytic bone metastases from several neoplasms. We report a case of bone metastases from bronchogenic carcinoma in a patient with TS bone changes. Reddit; Wechat; Abstract. Reddit; Wechat; Abstract. 1, 2 As metastases occur, the normally tempered osteoclasts are transformed into unruly bullies, proliferating and resorbing bone with abandon. I hope I never meet any of you or your families. The pain is unending even when using extremely high doses of every narcotic in my arsenal. Cookies help us deliver our Services. Reddit; Wechat; INTRODUCTION. What do you do? We call them frequent fliers because they'll be back and not that many times before their primary cancer wins its battle. Bone metastases were found in the spine (46.7%) and pelvis (42.7%). The treatment of bone metastases comprises a large part of the radiotherapy daily practice. Pinterest Reddit Tumblr Digg More. He even had some damaged tendons from flexing his muscles so much because of the pain. Press J to jump to the feed. Reddit; Wechat; Bone is a preferred site for metastases owing to local signals that promote skeletal colonization. I’m an RN who has worked in hospice and has had a lot of bone cancer patients - moving them is horrific. 16. Introduction In solid tumours, bone metastasis most commonly happen in prostate, breast and lung cancers. Fuck cancer. The findings were published in … Metastasis to bone from carcinoma of the thyroid was noted in 33 (12.7%) of 259 patients referred to the Nuclear Medicine Section of the University of California Medical Center, San Francisco from 1945 through 1964. I never said it in my original post, but cancer fucking sucks y'all. As someone with no knowledge on radiation or how it works, could you elaborate on how radiation helps with the pain? Based on favorable experience in other cancers with bone metastases and the lack of effective treatment, we started to use zoledronic acid (ZA), a recently developed synthetic bisphosphonate drug, in the treatment of this disease. • Posted by u/[deleted] 2 months ago. Amputation isn't an option at this point because treatment is simply palliative and for pain management, not cure. This study evaluated the number and timing of SREs from case studies to identify these factors. The clinical records, scintigrams, radiographic skeletal surveys, and bone marrow aspiration and trephine results of 30 children with neuroblastoma were reviewed to determine the relationship between the result of the scintigram and the clinical outcome of the patient. Bone metastases are a common clinical problem that is associated with the potential for significant symptoms such as pain, pathologic fracture, spinal cord compression, and hypercalcemia. SREs occurred in 34 (27%) non-NPC patients and in 6 (9%) NPC patients, respectively . When literally a hole is punched in the bone. In vertebra spine, bone metastasis can cause catastrophic compression fracture (bone fracture that compresses the spinal cord) which leads to: paraplegia (paralysis of both lower legs) quadriplegia (paralysis of both upper and lower limbs if compression fracture happened at higher… I’ve had patients with this diagnosis but... thought of it as like, tumors growing on the bones? To determine the characteristics of patients with germ cell cancer and bone metastases. Press question mark to learn the rest of the keyboard shortcuts. X-rays showed holes throughout his bones. Both bone properties and the tumor-intrinsic traits are associated with the metastatic propensity to bone (i.e., the bone tropism). Bone‐targeted agents can reduce the risk of SREs. r/Radiology. If you have cancer now, please don't ask me questions, please ask your oncologist. The opposite is most painful. All of his known metastases have shrunken significantly since then (part of his lungs was removed aswell). You could tell it was involuntary, and that she was consumed with misery. I’m so sorry for your loss. u/thellios. Palliative radiotherapy has proven to be successful in treating pain caused by metastatic lesions in any bone, and in treating neurological complaints caused by compression of the spinal cord due to lesions in the spinal column. Citing Literature. People i work with shine like Christmas trees. Reddit; Wechat; Abstract. However, the risk factors for SREs during BMA treatment are not well‐understood. Edit: Due to common repeated questions. This is one of those things. Toxic chemo did him in, as he suffered a heart attack. It’s the f’kin worst. My dad just died from this. As well as being in his lymph nodes and bladder. I still think about her 20 years later. I discussed my dad’s case in this thread. Close. He lasted only three months from diagnoses. This makes it a lot scarier. Only radiation and death are the way around the pain. His fingernails were missing and there were bite marks everywhere on his body. radiation and death are the way around the pain. Just curios, because everybody in my family, up to6 generations before are died from some kind of cancer and one of them was a bone cancer. My best mate died of it in 1988. Reddit; Wechat; Abstract. Posted by. Extensive bone cancer metastases!! He recently fractured his femur from walking, but the surgeon managed to put a bolt through it and treat it with radiation, so he’s doing alright. Bone metastases develop in approximately 30% to 40% of people with advanced NSCLC, with metastases either present at the time of diagnosis or developing during the course of the neoplastic disease. He was the toughest, strongest man I've ever known and by the time he passed away he was a thin withered husk. He’s only 65. Not into the bones. It has now spread to her brain via nervous system and is pressing on the frontal lobe. 77. Her last week has begun, the pain is extremely crazy and she is full on morphium if that even helps. Bone metastases, or osseous metastatic disease, is a category of cancer metastases that results from primary tumor invasion to bone.Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare. Abstract Although bone marrow examination is a common procedure in the evaluation of patients with cancer, its role and contribution have been questioned in recent years. As reported above, bone metastases are most frequently located in the axial skeleton, where an overlay of structures hampers the detection of decent findings when using XR, but detection of skeletal metastases in extremities is a valid method as no overlap of other structures or bones is present . She moaned in agony constantly. Metastases preferentially target the lymph nodes, lung, liver, or bone. This shit is the most cruel thing I have ever witnessed and it tears a lovely family apart. , so is there any way to completely cure a cancer in a stage when rapid cell mutation already started?Also example of a opposite kind of bone cancer, this is a slow process, not like a just hole suddenly appeared in a bone? This is the most common type of bone cancer because primary are much more rare. Is amputation a valid choice or does it spread quickly? I've never felt more sorry for a person in my life. That is a kind of bone cancer. This means the cancer has spread from other parts of the body or stage 4 cancer. She is losing her mind, voice and ability to speak/understand. Things that make you say "What the F*ck". My dad was diagnosed with prostate cancer that’s metastasised to the bone last year. Les métastases osseuses peuvent causer une morbidité importante, notamment de la douleur, des difficultés ambulatoires et une indépendance fonctionnelle réduite. Press question mark to learn the rest of the keyboard shortcuts. Abstract Purpose: To evaluate whether enhancement on serial dynamic gadolinium‐enhanced abdominal–pelvic MR imaging (DCE‐MRI) can determine the acuity of bone metastases… Somehow that makes it worse. Oh wow. Hopefully they were able to make him comfortable. Skeletal-related events and pattern of care. Malignancy (defined as metastatic disease) has been reported in nearly 5% of head and neck paragangliomas. That’s terrifying. User account menu. I'm specifically talking about bone metastasis. September 13, 2019. A look that implored me to help - yet there was no help I could offer. The pain he was in looked unbelievable. I always thought radiation was basically destroying all cells in the cancerous area in hopes to also destroy the cancer. By using our Services or clicking I agree, you agree to our use of cookies. Ten patients (53%) had solitary, and nine patients (47%) had multiple, sites of bone metastases. 6.1k points. Bisphosphonates were given as palliative therapy to 25 patients (33.3%). I don't know your diagnosis, prognosis, or current health status. Reddit; Wechat; Abstract. The mom of my gf is going through exactly what you mentioned right now. Unlike hematological malignancies that originate in the blood and form non-solid tumors, bone metastases generally arise from epithelial tumors and form a … Pain medicine cannot reach the pain. Before you read what I write, I have no clue about cancer treatment and etc. Bone metastases in patients with solid tumours (ST) and bone lesions in patients with haematological malignancies (HM) are common. The research team concluded that the B6Ca P line overcomes two critical limitations to study the skeletal metastasis of prostate cancer: PCa can now be studied in fully immunocompetent hosts and the injection produces bone metastases for scientists to study. Objective. Imaging of bone metastases may rely on nuclear medicine [bone scintigraphy or singlephoton emission computed tomography (SPECT), positron emission tomography (PET), PET-CT, or SPECT-CT], on radiograph-based technologies (radiographs and CT), and on MRI. Bone‐modifying agents (BMAs) reduce the incidence of skeletal‐related events (SREs) and are thus recommended for breast cancer patients with bone metastases. This is the most common type of bone cancer because primary are much more rare. Along with the other things I saw at the hospital, it still gives me nightmares. A consecutive series of 95 patients with hypernephroma was studied retrospectively after it was clinically suspected that there was a propensity for this tumor to metastasize to the scapula. Bone scintigraphy and magnetic resonance imaging are useful in distinguishing the TS bone lesions from bone metastases. They almost missed the fractures because of the cancer, and I know that eventually he’ll break something somewhere they can’t find or treat. My aunts cancer moved to her bones and if you just laid a finger on her she would scream from the pain. People i work with shine like Christmas trees. Whereas an increasing body of mechanistic studies expanded our understanding on bone tropism, they also revealed complexity across the bone lesions originated from different cancer types. Sorry to hear it. It’s cruel and horrific. Dr. Kenyon Meadows here, board-certified radiation oncologist with Southeast Georgia Health System Cancer Care Centers, and today’s video blog topic is bone metastases. Extensive bone cancer metastases!! Methods. Hypercalcemia was the most frequently observed SRE in the non-NPC patients … found bone metastases in 27 per cent of autopsied patients with carcinomas. Bone metastases in patients with metastatic renal cell carcinoma (mRCC) do not independently affect oncologic outcomes or survival, according to data presented at SUO 2020, a … Reddit; Wechat; Abstract. These tests may show bone metastases. Bone metastases were mainly localized to the spine (61%), pelvic bones (15%), ribs (8%) or other sites (16%), without significant differences between the NPC and the non-NPC patients. occur when cancer cells break off from a primary tumor that is somewhere else in the body INVESTIGATIONS ON the pathogenesis of cancer metastasis to bone have received increased attention by scientists worldwide. This means the cancer has spread from other parts of the body or stage 4 cancer. Is the contrast media responsible for the coloration? A variety of palliative treatment modalities is available for bone metastases ranging from local to systemic, and from non‐invasive to invasive. When I was in medical high school we had to practise at the Oncology department. A blessing really. Bone is a frequent site of metastases in many cancers. Cookies help us deliver our Services. I remember vividly the look on his face, the last time I went to see him. The case records of patients with known germ cell tumours (GCTs) within the Anglian Germ Cell Cancer Group database between January 2005 and March 2011 were reviewed retrospectively. Extensive bone cancer metastases!! We describe three patients with multiple silent bone metastases exhibiting a fatty halo at MRI that coexisted with expansive bone lesions. Yes, my 42 year old brother had the "opposite", multiple myeloma. 12 Osteoclasts are large, multinucleated cells with a specialized cell membrane (the “ruffled border”) that resorb bone, and osteoblasts are smaller, mononucleated cells that form new bone.
bone metastases reddit 2021